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Symetis, set up in January 2001, as a spin-off from the University of Zurich, is a a private Swiss company developing new transcatheter aortic valve implantation (TAVI) systems.

The company’s lead product, Acurate TA™, based on proprietary geometry and delivery technology, is currently in clinical trials and is well positioned to target the estimated $2 billion TAVI market. Acurate TA™ is on track to obtain CE market approval in 2011. In parallel, Symetis is conducting pre-clinical validation of Acurate TF™, a trans-femoral TAVI solution based on similar design principles, scheduled to enter clinical trials in 2011.

Truffle Capital first invested in Symetis in 2004 and is Symetis’ first shareholder.

Truffle Capital board member: Dr. Philippe Pouletty